Main Product

Native ChIP

Perfect for qPCR and next-generation sequencing

 

Chromatrap® Native ChIP kit provides an alternative to traditional cross-linked ChIP, which removes the need for fixing cells prior to extraction. Performing ChIP with native chromatin enables users to gain insights to histone and certain abundant transcription factors that are likely to be naturally bound to DNA.

This kit is designed to enable researchers to efficiently enrich chromatin and detect binding of low abundant transcription factors and histone modifications with superior selectivity and specificity from the smallest quantity of starting material. Since this unique filter-based kit contains no magnetic or agarose beads, users benefit from the inherent low background of a ChIP technology that performs faster and is dramatically easier to use than conventional kits.

Not sure if our Native ChIP kit is the right choice? Find out which Chromatrap® ChIP kit is best suited for you below.

FIND ME A CHROMATRAP® KIT

Preview
Features

Chromatrap Native ChIP sEQ

Bead-free System for ChIP

  • Maximum capture of the antibody-chromatin complex
  • Spin column format for maximum recovery of the enriched DNA

User-friendly Workflow

  • Quick and easy steps from start-to-finish
  • All reagents for 24 ChIP and 10 chromatin extractions supplied

Optimised DNA purification reagents

  • High quality NGS-ready ChIP DNA
Best for Sensitivity

Correctly orientated proteins for maximum chromatin-antibody binding and capture

Perfect for Low Samples

ChIP from as little as 1000 cells

ChIP in 5 Hours

No lengthy blocking or overnight steps 

Quality Sequencing Data

FASTQ > 30

Greater than 95% uniquely mapped reads for transcription factors and histone modifications

Products
Chromatrap Native ChIP-seq Protein A
Product Code : 500237
Chromatrap Native ChIP-seq Protein A
Product Code : 500237
Download Protocol

All reagents supplied to perform 24 bead-free Protein A, ChIP assays and up to 10 chromatin sample preparations by enzymatic digestion. DNA purification components included to obtain high quality DNA for NGS library preparation.

Chromatrap Native ChIP-seq Protein G
Product Code : 500238
Chromatrap Native ChIP-seq Protein G
Product Code : 500238
Download Protocol

All reagents supplied to perform 24 bead-free Protein G, ChIP assays and up to 10 chromatin sample preparations by enzymatic digestion. DNA purification components included to obtain high quality DNA for NGS library preparation.

Unsure about which product you need or looking for a formal quote?
Get advice from our team