Chromatrap® protocols differ from those used by other kit suppliers, including Active Motif, Diagenode, Cell Signalling Technology (CST), Abcam, Zymo Research and Epigentek, as these are all bead-based kits. It is therefore essential to study the protocols used by Chromatrap® first . We do not advise mixing buffers or washes from other manufacturers’ kits with Chromatrap® columns, as our superior solid-state chemistry may not be compatible with other kit components.